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OCR: Immunostaining of tumour sections wi confirmingantithyroglobulin antibody is helpful in Ited the follicular cell origin of the differenti carcinomas, particularly in metastases o ve reaction undetermined origin. Obtaining a positi ep in the with anticalcitonin is now an essential s homas (Fig. histological diagnosis of medullary carci o give a 16.15). The majority of these tumours al positive immunoreaction with anticarcinoembryonic antigen. Other immunoreactive peptides that are ostatin, occasionally demonstrable include som , known as gastrin-releasing peptide (or its fragmen ne (ACTH), bombesin), adrenocorticotrophic hormo and corticotrophin-releasing hormone,